Name Racecadrotil
Classes Gastrointestinal Agent
Antidiarrheal
Diseases Diarrhea
Gastrointestinal Disease

Racecadrotil

Racecadotril is a medication that belongs to the class of drugs called enkephalinase inhibitors. It works by decreasing the amount of fluid in the intestine, which helps to reduce diarrhea.

 

 

Racecadotril is indicated in-

  • Acute diarrhea in adults and children over 3 months of age.

 

 

  • The recommended adult and pediatric dose is 30 mg three times daily.
  • The maximum daily dose is 90 mg.
  • The dosage should be adjusted according to the age and weight of the child.
  • Racecadotril should be taken before meals.

 

 

Common side effects of Racecadotril include-

  • headache
  • abdominal pain
  • nausea
  • itching
 

 

 

  • Racecadotril should be used with caution in patients with moderate to severe renal impairment.
  • It should be avoided in cases of dehydration.
  • Racecadotril should not be used in patients with moderate to severe liver impairment.
  • Patient with history of angioedema of any other aetiology should be cautious.
  • Administer racecadotril in combination with rehydration therapy.
  • Avoid use in case of prolonged vomiting.
  • Concomitant use with ACE inhibitors should be avoided.

 

 

Contraindication

  • Hypersensitivity to the active substance or to any of the excipients

 

 

Racecadotril is contraindicated in-

  • Severe liver dysfunction
  • Children under 3 months of age