Cyclobenzaprine Hydrochloride is indicated as an adjunct to rest and physical therapy for the relief of muscle spasm associated with acute, painful musculoskeletal conditions.

Muscle Spasm

For the majority of patients, the suggested dosage of Cyclobenzaprine Hydrochloride is 5 mg thrice daily. Depending on the individual's response to the medication, the dosage can be raised to 10 mg thrice daily. The use of Cyclobenzaprine Hydrochloride beyond two or three weeks is not advisable.

Adverse reactions associated with Cyclobenzaprine Hydrochloride include-

• Drowsiness
• Dry mouth
• Dizziness
• Fatigue
• Headache
• Nausea
• Constipation

Drowsiness

Dry Mouth

Dizziness

Fatigue

• Sedation: Cyclobenzaprine Hydrochloride may cause significant sedation. Advise patients to avoid activities requiring mental alertness or coordination, such as driving or operating machinery.
• Alcohol and CNS Depressants: Avoid concomitant use with alcohol or other central nervous system (CNS) depressants, as additive sedative effects may occur.
• Serotonin Syndrome: Monitor for signs of serotonin syndrome, especially when used concomitantly with serotonergic drugs. Symptoms may include mental status changes, autonomic instability, and neuromuscular abnormalities.
• Cardiovascular Effects: Use with caution in patients with a history of cardiovascular disease, as cyclobenzaprine may have potential effects on the cardiac conduction system.
• Hepatic Impairment: Use with caution in patients with hepatic impairment. Dosage adjustments may be necessary.
• Acute Angle-Closure Glaucoma: Cyclobenzaprine may increase intraocular pressure. Use cautiously in patients with narrow-angle glaucoma.