Cefazoline+Lidocaine is indicated for the treatment and prophylaxis of bacterial infections in patients undergoing surgical procedures. It is effective against a range of susceptible gram-positive and gram-negative microorganisms, including staphylococci, streptococci, and E. coli. Lidocaine is included in this combination to provide local anesthesia, which reduces the pain associated with intramuscular injection of cefazolin.

Surgical prophylaxis

The recommended dosage of Ancef-Lido varies depending on the patient's age, weight, and the severity of the infection being treated. It is usually given as an intramuscular injection. The typical adult dosage is 1 to 2 grams of cefazolin, combined with 20 to 40 mg of lidocaine, injected into a large muscle every 6 to 8 hours.

For pediatric patients, the dosage is determined by body weight. The usual dosage is 25 to 50 mg per kg of body weight of cefazolin, combined with 0.5 to 1 mg per kg of body weight of lidocaine, injected into a large muscle every 6 to 8 hours.

Common adverse reactions associated with Cefazoline+Lidocaine include-

• pain
• swelling
• redness at the injection site.

Other adverse reactions may include-

• fever
• rash
• nausea
• vomiting
• diarrhea

Pain at injection site

Diarrhea

Skin redness

Fever

Cefazoline+Lidocaine should be used with caution in patients with a history of liver or kidney disease, as cefazolin is primarily eliminated through the kidneys. Patients with a history of bleeding disorders may also be at increased risk for bleeding at the injection site due to the inclusion of lidocaine. Cefazoline+Lidocaine should be used with caution in these patients.