Name Erythromycin Thiocyanate + Sulphadiazine + Trimethoprim
Classes Antiinfective Agent
Antibiotic
Antibiotic Combination
Diseases Broncho Pneumonia
Cholera
Colisepticemia
Coryza
Chronic Respiratory Disease (CRD)
Enteritis
Fowl Typhoid
Pullorum Disease
Veterinary Infection

Erythromycin Thiocyanate + Sulphadiazine + Trimethoprim

Erythromycin Thiocyanate + Sulphadiazine + Trimethoprim is a broad-spectrum antibiotic for veterinary use. Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by binding to the 50S subunit of the bacterial ribosome. Sulphadiazine is a sulfonamide antibiotic that inhibits bacterial folic acid synthesis. Trimethoprim is a diaminopyrimidine antibiotic that inhibits bacterial folate metabolism by inhibiting dihydrofolate reductase.

 

Erythromycin, Sulphadiazine & Trimethoprim is indicated in infectious coryza, fowl cholera, fowl typhoid, pullorum disease, chronic respiratory disease (CRD), Colisepticemia and enteritis of poultry.

 

0.5-1 g/litter of drinking water continues for 3-5 consecutive days, dose may be increased or decreased according to the severity of infection or as directed by the registered veterinarian.

 

The combination is well tolerated and does not show any side effect in poultry at the recommended dose.

 

  • Erythromycin Thiocyanate + Sulphadiazine + Trimethoprim should only be used in animals with bacterial infections that are susceptible to the combination of the three antibiotics.
  • Use of the drug in non-target animals or in excessive doses may lead to bacterial resistance and superinfections.
  • The drug should not be used in animals with known hypersensitivity to any of the active ingredients or other sulfonamides.
  • The drug should be used with caution in animals with hepatic or renal impairment.
  • The drug should not be administered to animals intended for human consumption within 10 days of the last dose.

 

Contraindication

Erythromycin Thiocyanate + Sulphadiazine + Trimethoprim is contraindicated in animals with hypersensitivity to any of the active ingredients or other sulfonamides.