Cyproterone acetate + Ethinylestradiol is a contraceptive used to prevent pregnancy.

Prevention of Pregnancy

• Take one tablet daily by mouth at the same time every day. 
• Tablets must be taken in the order directed on the blister pack.

The following adverse reactions have been reported with the use of Cyproterone acetate + Ethinylestradiol:

• Nausea
• Headache
• Breast tenderness
• Irregular vaginal bleeding or spotting
• Weight changes
• Mood changes
• Decreased libido
• Vaginal discharge
• Skin rash or hives
• Fluid retention/ edema
• High blood pressure
• Blood clots

Nausea	Headache	Mood Disorder
Breast Tenderness	Abdominal Cramp	Edema

• Vascular risks: Stop Yasmin if a thrombotic event occurs. Stop at least 4 weeks before and through 2 weeks after major surgery. Start no earlier than 4 weeks after delivery, in women who are not breastfeeding 
• Combined oral contraceptivess containing Drospirenone and ethinyl estradiol may be associated with a higher risk of venous thromboembolism (VTE) than Combined oral contraceptivess containing levonorgestrel or some other progestins. Before initiating Yasmin in a new Combined oral contraceptives user or a woman who is switching from a contraceptive that does not contain Drospirenone and ethinyl estradiol, consider the risks and benefits of a Drospirenone and ethinyl estradiol-containing Combined oral contraceptives in light of her risk of a VTE
• Hyperkalemia: Drospirenone and ethinyl estradiol has anti-mineralocorticoid activity. Do not use in patients predisposed to hyperkalemia. Check serum potassium concentration during the first treatment cycle in women on long-term treatment with medications that may increase serum potassium concentration. 
• Liver disease: Discontinue Yasmin if jaundice occurs.
• High blood pressure: Do not prescribe Yasmin for women with uncontrolled hypertension or hypertension with vascular disease. 
• Carbohydrate and lipid metabolic effects: Monitor prediabetic and diabetic women taking Yasmin. Consider an alternate contraceptive method for women with uncontrolled dyslipidemia.
• Headache: Evaluate significant change in headaches and discontinue Yasmin if indicated. 
• Uterine bleeding: Evaluate irregular bleeding or amenorrhea.