Name Vitamin D
Classes Nutritional Supplement
Vitamin
Diseases Fanconi Syndrome
Hypophosphatemia
Malnutrition
Rickettsia
Soft Bone
Vitamin D Deficiency

Vitamin D

Vitamin D or cholecalciferol, is a fat soluble vitamin that helps the body to absorb calcium and phosphate. It plays an important role in bone and teeth formation. It also minimizes the severity of bacterial infections, improves lung function, lowers the risk of cancer (breast, colorectal), and aids in the maintenance of adequate insulin levels in type 2 diabetes patients.

Vitamin D preparations are indicated for the following conditions-

  • Vitamin D deficiency
  • Osteoporosis
  • Osteomalacia
  • Hypocalcemia
  • Tetany & Ricketts ( with deficiency of vitamin D3)

For capsule: Adults:

  • Treatment of Vitamin D3 deficiency: 40000 IU once weekly for 7 weeks. Doses for maintenance therapy is 1400-2000 IU/day. To confirm the target level of 25 hydroxyvitamin D, measurement of it should be determined 3-4 months after initiating the maintenance therapy.
  • Prevention of Vitamin D3 deficiency: 20000 IU every 4 weeks. Higher doses may be required in certain situations.
  • Addition to specific therapy for osteoporosis: 20000 IU once a month.

For capsule: Children (12-18 years):

  • Treatment of Vitamin D3 deficiency: 20000 IU once every 2 weeks for 6 weeks.
  • Prevention of Vitamin D3 deficiency: 20000 IU every 6 weeks.

For film-coated tablet: 1000 IU (1-2 tablets) daily, or as directed by physician. Take the medicine with food or within 1 hour after a meal.

For oroflash or chewable tablets: 1000 IU to 2000 IU daily, or as directed by physician. Take the medicine with food or within 1 hour after a meal. Place the tablet in mouth swallow after chewing.

For Syrup:
For patients with risk of Cholecalciferol deficiency:

  • 0-1 yr: 400 IU/ day (2 ml)
  • >1 Yr: 600 lU/ day (3 ml)

For Cholecalciferol deficient patients:

  • 0-1 yr: 2000 IU/ day (+50000 IU/week ) for 6 weeks
  • 1 -18 yrs: 2000 IU/ day for 6 weeks.

Injection: Prevention: 

  • Infants receiving Vitamin D enriched milk: 1/2 ampoule (0.5ml) i.e. 1,00000 I.U. every 6 months.
  • Nursed infants or infants not receiving Vitamin D enriched milk or young children up to 5 years of age: 1 ampoule (1ml) i.e. 2,00000 I.U. every 6 months.
  • Adolescents: 1 ampoule (1ml) i.e. 2,00000 I.U. every 6 months during winter.
  • Pregnancy: 1/2 ampoule (0.5ml) i.e. 1,00000 I.U. from the 6th or 7th month of pregnancy.
  • Elderly: 1/2 ampoule (0.5ml) i.e. 1,00000 I.U. every 3 months. Digestive disorders, concomitant treatment with antiepileptics & other particular condition not described above; 1/2 ampoule (0.5ml) i.e. 1,00000 I.U. or 1 ampoule (1ml) i.e. 2,00000 I.U. every 3 or 6 months.

Injection: Vitamin D deficiency:

  • 1 ampoule (1ml) i.e. 2,00000 I.U. which can be repeated 1 to 6 months later. Or, as directed by the registered physician.

Side effects associated with the drug are-

  • Hypercalcemia
  • Hypercalciuria
  • Skin rash
  • Nausea
  • Urticaria
  • Pruritus

Caution is advised while treating patients with renal impairment.

Contraindication

Contraindicated in patients hypersensitive to any component of the formulation.

There is no known contraindications of the preparation in terms of food and drinks.