Toltrazuril is indicated for the prevention and treatment of coccidiosis caused by Eimeria spp. in poultry, turkeys, and calves.

Coccidiosis

• For oral administration via drinking water.
• • Poultry, turkeys : 100 ml per 100 litres of drinking water for continuous medication during 48 hours or 300 ml per 100 litres of drinking water for 8 hours each day during 2 days (= 7 mg toltrazuril per kg bodyweight).

• • Calves, sheep, goats, pigs : 0.8 ml (= 20 mg toltrazuril) per kg bodyweight during 2 days.

• In case of increased or lowered water intake adjust the medication concentrations accordingly, to obtain a daily dose of 7 mg toltrazuril per kg bodyweight. If necessary repeat after 5 days.
• Medicated drinking water should be used within 24 hours.

None known.

• Toltrazuril should not be administered to animals with known hypersensitivity to the drug.
• Use with caution in debilitated or dehydrated animals, as these may be more susceptible to adverse reactions.
• The safety of toltrazuril in pregnant or lactating animals has not been established.
• Use of toltrazuril in conjunction with other drugs that have an inhibitory effect on dihydrofolate reductase, such as trimethoprim and sulfonamides, may increase the risk of adverse reactions.
• Toltrazuril should not be used for the treatment of coccidiosis caused by species other than Eimeria spp.