Terazosin is indicated in the following conditions-

• Benign prostatic hyperplasia
• Hypertension

Benign prostatic hyperplasia (BPH)

Hypertension (High Blood Pressure)

Benign prostatic hyperplasia:

• Initial dose: All patients should begin with 1 mg at bedtime, and this dose should not be exceeded as an initial dose. Patients should be closely monitored during the initial administration to reduce the risk of a severe hypotensive response.
• Maintenance dose: To achieve the desired improvement in symptoms and/or flow rates, the dose should be gradually increased to 2 mg, 5 mg, or 10 mg once daily. For the clinical response, 10 mg once daily is usually required. As a result, a minimum of 4-6 weeks of treatment with 10 mg may be required to determine whether a beneficial response has been achieved. Despite appropriate titration, some patients may not achieve a clinical response.

Hypertension:

• Initial dose: All patients should begin with 1 mg at bedtime, and this dose should not be exceeded. This initial dosing regimen should be strictly followed to avoid severe hypotensive effects.
• Maintenance dose: To achieve the desired blood pressure response, the dose can be gradually increased. The typical recommended dose range is 1 mg to 5 mg once daily; however, some patients may benefit from doses as high as 20 mg per day. Doses greater than 20 mg do not appear to have an additional blood pressure effect, and doses greater than 40 mg have not been studied.

The most frequent reactions associated with Terazosin therapy are:

• dizziness 
• headache 
• drowsiness 
• asthenia
• weakness 
• palpitations
• nausea 

Dizziness	Headache	Drowsiness
Asthenia	Weakness	Nausea

• After the VERY FIRST DOSE, Terazosin can cause a sudden drop in blood pressure. You may feel dizzy, faint, or "light-headed" after getting out of bed or a chair. This is more likely to happen after the first few doses, but it can happen at any time while taking the drug.
• Terazosin and similar medications have rarely caused painful erections of the penis that last for hours and are unrelieved by sexual intercourse or masturbation. This is a serious condition that, if left untreated, can result in permanent inability to have an erection. If you have a prolonged abnormal erection, contact your doctor or go to the emergency room right away.
• Many of the symptoms of prostate cancer and BPH are the same. These two diseases are frequently found together. Patients suspected of having BPH should be examined before beginning Terazosin therapy to rule out the presence of prostate cancer.
• During cataract surgery, some patients on/or previously treated with alpha-1 blockers experienced intraoperative floppy iris syndrome (IFIS).