Sennosides are indicated for the treatment of constipation. They are commonly used to provide short-term relief and prevent complications associated with prolonged constipation, such as fecal impaction.

Constipation

Dosage recommendations may vary based on the specific product and formulation. The following is a general guideline.

1. Adults:

   • The usual oral dosage is 8.6 mg to 60 mg once daily, preferably at bedtime.
   • The dosage may be adjusted based on individual response and the severity of constipation.

2. Children (6 to 12 years):

   • The recommended oral dosage is typically lower, ranging from 4.3 mg to 30 mg once daily at bedtime.

3. Children (2 to 6 years):

   • Lower dosages, often in the range of 2.1 mg to 15 mg, may be appropriate for this age group.

Adverse reactions are listed from most common to least common:

• Abdominal cramps
• Diarrhea
• Nausea
• Dehydration (in severe cases or with prolonged use)

Abdominal Pain

Diarrhea

Nausea

Dehydration

• Dehydration: Sennosides can lead to fluid loss, and patients should be advised to maintain adequate hydration during treatment.
• Abdominal Pain: Persistent or severe abdominal pain may indicate a more serious condition, and medical attention should be sought.
• Prolonged Use: Prolonged use of stimulant laxatives, including sennosides, should be avoided without medical supervision.