Amoxicillin is indicated for the following diseases-

• Infections of the Ear, Nose, and Throat
• Infections of the Genitourinary Tract
• Infections of the Skin and Skin Structure
• Infections of the Lower Respiratory Tract
• Helicobacter pylori Infection

Pharyngitis

UTI (Urinary Tract Infection)

Respiratory infections

Skin Infection

Amoxicillin is available as capsules, oral drops, injection and powder for suspension.

Adult: 250 mg three times daily, increasing up to 500 mg three times daily for severe infections.

Children (up to 10 years of age) : 125 mg three times daily, increasing up to 250 mg three times daily for severe infections.

• Severe or recurrent purulent respiratory infection: 3 gm every 12 hours.
• Otitis media: Recommended dose is 1 g three times daily for adult and 40 mg/kg body weight daily in 3 divided doses for children (max. 3 g daily).
• Pneumonia: Recommended dose is 500-1000 mg three times daily.
• Dental abscess: Recommended dose is 3 gm, repeated after 10-12 hours.
• Urinary tract infections: Recommended dose is 3 gm, repeated after 10-12 hours.
• Gonorrhoea: Single dose of 2-3 gm with Probenecid 1 gm is recommended (Probenecid is contraindicated in children under 2 years).
• In renal impairment: it may be necessary to reduce the total daily dosage.

The side effects of amoxicillin is usually mild. The most common side effects are-

• Diarrhea
• Nausea
• Rash
• Pseudomembranous colitis

Diarrhea

Nausea

Rash

Pseudomembranous collitis

• Some patients may show hypersensitivity reactions to ampicillin. In such cases treatment should be stopped immediately.
• Superinfection of resistant organisms like C.difficile may occur.
• Dosage should be adjusted for renally impaired patients.