Medicine details
| Image |  |
| Name | Co-Diovan 160/12.5 |
| Dosage | Tablet |
| Generic Name | Hydrochlorothiazide + Valsartan |
| Classes |
Cardiovascular Agent Antihypertensive Antihypertensive Combination |
| Diseases |
Cardiovascular Disease Hypertension (High Blood Pressure) |
| Company | Novartis (Bangladesh) Ltd. |
Drug Package Details
| Strength | 12.5 mg + 160 mg |
| Storage Condition | |
| Origin Country | Bangladesh |
| Commercial Pack | 28 |
| Price per pack | ৳ 1,853.60 |
| Cost per pack | ৳ 1,631.17 |
| Package unit | 14 tabs strip |
| Price per unit | ৳ 66.20 |
| Cost per unit | ৳ 58.26 |
| Discount | 0 |
| Coupon | |
| Remarks |
Hydrochlorothiazide + Valsartan
Hydrochlorothiazide + Valsartan is a combination of valsartan, an orally active, AT1 receptor subtype specific angiotensin II receptor blocker (ARB), and hydrochlorothiazide, a diuretic.
This combination is used to treat Hypertension.
- Hydrochlorothiazide + Valsartan is available as tablets.
- Hydrochlorothiazide + Valsartan 160/12.5 mg once day is the usual beginning dose. After 1 to 2 weeks of therapy, the dosage can be increased to a maximum of one 320/25 tablet once day as needed to regulate blood pressure. After a dosage modification, the maximum antihypertensive effects are achieved in 2 to 4 weeks.
The side effects associated with the medication are as follows-
- headache
- dizziness
- Pharyngitis
- Hypotension
- Tinnitus
- Dyspepesia
- Asthenia
- During the second and third trimesters of pregnancy, medications that act on the renin-angiotensin system impair fetal renal function and increase fetal and newborn morbidity and death.
- In controlled trials, patients with uncomplicated hypertension treated with Hydrochlorothiazide + Valsartan experienced a very little (0.7 percent) drop in blood pressure. Symptomatic hypotension can occur in patients with an active renin-angiotensin system, such as volume- and/or salt-depleted patients on high doses of diuretics.
Contraindication
- Contraindicated to the patients who are sensitive to hydrochlorothiazide or to other sulfonamide-derived drugs, such as-
- Contraindicated to the patients who are sensitive to valsartan or other ARBs, such as-
- Concomitant use of Hydrochlorothiazide + Valsartan with aliskiren containing products in patients with diabetes mellitus or renal impairment.
- Hydrochlorothiazide + Valsartan is contraindicated in pregnancy.
- Hydrochlorothiazide + Valsartan is contraindicated in patients with severe kidney problems (GFR 30 mL/min) and anuria due to the hydrochlorothiazide component.
- Hydrochlorothiazide + Valsartan is contraindicated in patients with significant hepatic problems or biliary cirrhosis and cholestasis due to the valsartan component.
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